The low fat/low cholesterol diet is ineffective

Is the metabolic syndrome caused by a high fructose, and relatively low fat, low cholesterol diet?

The metabolic syndrome (MetS) is manifested by a lipid triad which includes elevated serum triglycerides, small LDL particles, and low high-density lipoprotein (HDL) cholesterol, by central obesity (central adiposity), insulin resistance, glucose intolerance and elevated blood pressure, and it is associated with an increased risk of type 2 diabetes and coronary heart disease. We have developed ...

Food for prevention of coronary heart disease: Beyond the low fat, low cholesterol diet.

The single major cause of death throughout the world is coronary heart disease. Prevalence is stable or decreasing in North America, Australasia and most of Europe, while rapidly increasing in eastern Europe, Asia and Africa. Atherosclerosis is the underlying pathology. This is one of the classic lifestyle diseases on the background of genetic susceptibility. Diet plays a key role in the initia...

Resveratrol protects against diet-induced atherosclerosis by reducing low-density lipoprotein cholesterol and inhibiting inflammation in apolipoprotein E-deficient mice

Objective(s):Resveratrol (RES) is a polyphenol compound that has been shown a promising cardioprotective effect. However, some reports have yielded conflicting findings. Herein, we investigated the anti-atherosclerotic effects of RES in apolipoprotein E (apo E)-deficient mice on a high cholesterol diet. Materials and Methods: Firstly, atherosclerosis was induced by feeding a high cholesterol di...

Hepatic Lipid Accumulation by High Cholesterol Diet is Inhibited by the Low Dose Fish Oil in Male C57BL/6J Mice

high cholesterol diet increases expression of cholesterol 24-hydroxylase and bace1 in rat hippocampi: implications for the effect of diet cholesterol on memory

background abnormal cholesterol homeostasis is associated with the pathogenesis of neurodegenerative disease and cognitive impairment. objectives our objective was to evaluate changes in the expression of proteins related to cognition and cholesterol homeostasis in the hippocampi of rats as well as behavioral modifications following the administration of a cholesterol-rich diet. methods in this...